Neutropenia in Psychiatric Out-Patients.
- Author:
Hyeun Chul BAIK
1
;
Doh Joon YOON
;
Hwi Joong YOON
;
Geon Ho BAHN
Author Information
1. Department of Neuropsychiatry, KyungHee University Hospital, Seoul, Korea. behav@unitel.co.kr
- Publication Type:Original Article
- Keywords:
Neutropenia;
Psychotrophic drug;
Psychiatric out-patient;
CBC/DC
- MeSH:
Blood Cell Count;
Carbamazepine;
Clozapine;
Follow-Up Studies;
Humans;
Neuropsychiatry;
Neutropenia*;
Neutrophils;
Outpatients*;
Phenytoin;
Psychotropic Drugs;
Valproic Acid
- From:Korean Journal of Psychopharmacology
2002;13(3):148-153
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECT: The study was performed to examine the psychotrophic drugs used in psychiatric out-patients in which neutropenia developed and current state of consultation and to confirm the importance of complete blood count and differential count (CBC/DC). SUBJECTS AND METHODS: The subjects were 60 patients of our university hospital in which neutropenia developed in out-patient department (OPD) of psychiatry during recent three years. The absolute neutrophil counts of patient were below 2,000/mm3. RESULTS: The reasons why exam was performed were mainly to follow-up exam during medications. Mood stabilizers such as carbamazepine, phenytoin, sodium valproate were identified to cause neutropenia in the group using multiple drugs, and clozapine was highly related in the group using single drug. But many kinds of drugs were related with neutropenia. We have not checked well enough the CBC/DC and have not consulted well to hematologist in OPD of neuropsychiatry. CONCLUSIONS: It is important to find neutropenia in the psychiatric out-patients using psychotropic drugs. We had better check CBC/DC routinely and consult to hematologist.
