The Predictive Factors of Treatment Effects in Children with Attention Deficit Hyperactivity Disorder.
- Author:
Jong Bum LEE
1
;
Hyung Mo SUNG
;
Seung Deuk CHEUNG
;
Jin Sung KIM
;
Wan Seok SEO
;
Dai Seg BAI
;
Eun Jung JUNG
;
Hyung Bae PARK
Author Information
1. Department of Psychiatry, College of Medicine, Yeungnam University, Daegu, Korea.
- Publication Type:Original Article
- Keywords:
ADHD;
Methylphenidate;
Predictive factors
- MeSH:
Anxiety;
Attention Deficit Disorder with Hyperactivity*;
Child*;
Depression;
Executive Function;
Female;
Humans;
Intelligence;
Methylphenidate
- From:Korean Journal of Psychopharmacology
2002;13(3):170-193
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
This study examined 60 children with ADHD through K-ABC, ADDES-HV, ADD-H comprehensive teacher's rating scale (ACTeRS), CAP, SNAP, Academic Performance rating scale, K-PIC, CPT and WCST in order to estimate the effects of methylphenidate, and find out various factors which can influence on treatment responses and predictive factors of treatment. Boys showed better improvement in impulsiveness of behavior symptoms than girls, but girls showed better improvement in trials to completed the first category in WCST. In the aspect of age, the lower graders (age 7-9) showed improvement in sequential processing ability of intelligence but the higher graders (age 10-12) showed deterioration. In the aspect of sub-categories of ADHD, children with mixed type who had been worse in attention deficit and behavior symptoms in pretreatment state, showed significantly higher improvement than children with predominantly inattentive type in every scopes of behavior symptom check list. And in clusters of K-PIC, after treatments the group those who had have more anxiety or depression showed better improvement in omission error in CPT. In the aspect of intelligence level, children with average intelligence showed better improvement in impulsiveness and impulse control than the rests. In the aspect of executive functions, the less omission errors in CPT one made, the better improvement in attention and academic ability he showed. And the less perseverative response in WCST one had, the better improvement in hyperactivity he showed however his simultaneous processing abilities were deteriorated. With these results, this study confirms that methylphenidate is effective in behavior symptoms, academic performance, intelligence and various performance abilities of children with ADHD including attention and response control. In the cases of the children with severe ADHD symptoms, especially behavioral disinhibition and the children with mixed type of ADHD, it is considered useful to predict the results of treatments.
