Probiotic mixture VSL#3 prevents ulcerative colitis-associated carcinogenesis in mice and cells by regulating the inflammatory and Wnt/β-catenin pathway.

Author: Wenbin LI ¹ ; Yanan WANG ¹ ; Chunsaier WANG ¹ ; Hongying WANG ² ; Yiming MA ² ; Hong YANG ¹ ; Xinhua ZHAO ² ; Xiaomin HU ³ ; John Y KAO ⁴ ; Jiaming QIAN ¹ ; Chung OWYANG ⁴ ; Jingnan LI ¹
Author Information

1. Department of Gastroenterology, Key Laboratory of Gut Microbiota Translational Medicine Research, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
2. National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
3. Department of Central Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
4. Department of Internal Medicine, Division of Gastroenterology, University of Michigan Health System, Ann Arbor, MI, USA.
Publication Type:Journal Article
MeSH: Animals; Mice; Colitis, Ulcerative/metabolism*; beta Catenin; Carcinogenesis; Probiotics; Colitis/metabolism*
From: Chinese Medical Journal 2022;135(19):2357-2359
CountryChina
Language:English