Selection and application of explanatory and pragmatic randomized controlled trials in clinical research of acupuncture.
10.13703/j.0255-2930.20211103-k0002
- Author:
Rui-Min JIAO
1
;
Wei-Juan GANG
1
;
Yu-Qing ZHANG
2
,
3
,
4
;
Xiang-Hong JING
1
Author Information
1. Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China.
2. Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China
3. Department of Clinical Epidemiology and Biostatistics, McMaster University, Canada
4. Ningbo Nottingham GRADE Center, University of Nottingham.
- Publication Type:Journal Article
- Keywords:
acupuncture;
clinical research methodology;
explanatory randomized controlled trial;
pragmatic randomized controlled trial
- MeSH:
Acupuncture Therapy/methods*;
Randomized Controlled Trials as Topic
- From:
Chinese Acupuncture & Moxibustion
2022;42(9):1073-1077
- CountryChina
- Language:Chinese
-
Abstract:
In the view of the controversy that there is no efficacy difference between true and sham acupuncture in acupuncture randomized controlled trials (RCTs), it is analyzed that one of the reasons is that many clinical studies do not properly understand the design of RCT research and interpret the research results. Starting from the concept and coverage of explanatory RCT and pragmatic RCT, this study lists the application examples of two types of RCTs in the field of acupuncture from five aspects: research purpose and trial environment, subject selection, intervention measures, control measures and outcome evaluation, so as to provide some ideas for their application in clinical trials.
