Value of
10.3969/j.issn.1001-5256.2022.12.017
- VernacularTitle:F-FDG PET/CT、超声造影及联合应用对胰腺良恶性病变的鉴别诊断价值比较
- Author:
Lichun ZHENG
1
;
Xiaoming ZHANG
1
;
Tianying YU
1
;
Jie LI
2
;
Xiaoqian DENG
3
;
Xiangliu OUYANG
3
Author Information
1. Department of Nuclear Medicine, Tangshan Gongren Hospital, Tangshan, Hebei, 063000, China
2. Department of Gynaecology and Obstetrics, Tangshan Gongren Hospital, Tangshan, Hebei, 063000, China
3. Department of Ultrasound, Tangshan Gongren Hospital, Tangshan, Hebei, 063000, China
- Publication Type:Original Articles_Pancreatic Diseases
- Keywords:
Pancreatic Neoplasms;
Positron Emission Tomography Computed Tomography;
Tomography, X-Ray Computed;
Fluorodeoxyglucose F18
- From:
Journal of Clinical Hepatology
2022;38(12):2774-2779
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the value of 18 F-FDG PET/CT, contrast-enhanced ultrasound, and their combination in the differential diagnosis of benign and malignant pancreatic lesions. Methods A retrospective analysis was performed on patients with pancreatic lesions who underwent 18 F-FDG PET/CT and contrast-enhanced ultrasound who were admitted to Tangshan Gongren Hospital from January 2015 to December 2020. The imaging results were confirmed by pathology examination to evaluate diagnostic sensitivity, specificity, accuracy, positive and negative predictive value. The t -test was used for comparison of continuous data between two groups, and the chi-square test was used for comparison of categorical data between groups. Results There were 83 malignant lesions and 25 benign lesions in 108 patients. The sensitivity, specificity, accuracy, positive and negative predictive value were 86.75%, 80.00%, 85.19%, 93.51% and 64.52% for 18 F-FDG PET/CT; and 69.88%, 76.00%, 71.30%, 90.63% and 43.18% for contrast-enhanced ultrasound, respectively. The two methods differed significantly in sensitivity and accuracy (all P < 0.05), but not in specificity, negative and positive predictive value (all P > 0.05). When combined with the contrast-enhanced ultrasound, 18 F-FDG PET/CT had an increased sensitivity, specificity, accuracy, positive and negative predictive value of 90.36%, 84.00%, 88.89%, 94.94% and 72.41%, respectively, though this was not statistically significant due to the increased signal of blood supply in the lesions. Conclusion 18 F-FDG PET/CT has a better performance than contrast-enhanced ultrasound in the differential diagnosis of benign and malignant pancreatic lesions, and their combination can improve the diagnostic value.
