Insulin and Insulin Resistance in Diabetes with Cognitive Dysfunction (review)
10.3969/j.issn.1006-9771.2015.01.011
- VernacularTitle:胰岛素及胰岛素抵抗与糖尿病认知功能障碍
- Author:
Leilei GUO
;
Guoqing TIAN
- Publication Type:Journal Article
- Keywords:
diabetes mellitus, cognition, insulin, insulin resistance, hyperinsulinemia, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2012;18(5):433-435
- CountryChina
- Language:Chinese
-
Abstract:
Learning and memory dysfunction caused by diabetes is gaining an increased attention. Diabetes can significantly increasethe risk of dementia, including vascular dementia and Alzheimer's disease; and diabetes itself can lead to mild or moderate cognition decline.Many clinical and experimental datas indicated that deficiency of insulin or insulin resistance can significantly reduce the threshold of cognitivedysfunction and accelerate the progress of cognitive decline. This paper reviewed the effect of insulin and insulin resistance on cognitivefunction in diabetes.
