Effects of Morroniside on Cycloxygenase after Platelet Aggregation Induced by Adenosine Diphosphate in Rabbits

VernacularTitle:莫诺苷对二磷酸腺苷诱导兔血小板聚集后环氧酶的影响
Author: Panli SUN ; Shourong WEI ; Xiaofeng WANG ; Wen WANG ; Naihong CHEN ; Cunkuan XUE ; Hao LIU
Publication Type:Journal Article
Keywords: morroniside, platelet aggregation, cycloxygenase, rabbits
From: Chinese Journal of Rehabilitation Theory and Practice 2012;18(4):331-332
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of morroniside on cycloxygenase (Cox) in the condition of platelet aggregation inducedby adenosine diphosphate (ADP) in rabbits. Methods The levels of Cox induced by ADP in different groups were detected by enzyme-linked immunosorbent assay (ELISA). Results Compared with the control group, all the morroniside groups significantly inhibited theincrease of Cox induced by ADP (P<0.001), which had concentration dependence, and the inhibition rate of high dose group was 30%. ConclusionMorroniside can decrease the level of Cox and it may be the mechanism of morroniside on inhibiting the platelet aggregation inducedby ADP in rabbits.