Effects of Morroniside on Inhibiting Thromboxane B2 after Platelet Aggregation Induced by Adenosine Diphosphate in Rabbits
10.3969/j.issn.1006-9771.2012.04.004
- VernacularTitle:莫诺苷对二磷酸腺苷诱导兔血小板聚集后血栓素B2的影响
- Author:
Wei ZUO
;
Xiaofeng WANG
;
Houxi AI
;
Li ZHANG
;
Hui JI
;
Naihong CHEN
;
Wen WANG
- Publication Type:Journal Article
- Keywords:
morroniside, platelet aggregation, thromboxane B2, rabbits
- From:
Chinese Journal of Rehabilitation Theory and Practice
2012;18(4):329-330
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of morroniside on thromboxane B2 in the condition of platelet aggregation in rabbits inducedby adenosine diphosphate (ADP). Methods The level of TXB2 was determined by enzyme-linked immunosorbent assay (ELISA). ResultsCompared with the controls, morroniside significantly inhibited the increase of TXB2 induced by ADP (P<0.001). Conclusion Morronisidecan inhibit the level of TXB2 by inhibiting the platelet aggregation in rabbits induced by ADP.