Progress of Polysaccharide-Contained Polyurethanes for Biomedical Applications
10.1007/s13770-022-00464-2
- Author:
Do-Bin JU
1
;
Jeong-Cheol LEE
;
Soo-Kyung HWANG
;
Chong-Su CHO
;
Hyun-Joong KIM
Author Information
1. Department of Agricultural Biotechnology, Seoul National University, Seoul 08824, Korea
- Publication Type:REVIEW ARTICLE
- From:
Tissue Engineering and Regenerative Medicine
2022;19(5):891-912
- CountryRepublic of Korea
- Language:English
-
Abstract:
Polyurethane (PU) has been widely examined and used for biomedical applications, such as catheters, blood oxygenators, stents, cardiac valves, drug delivery carriers, dialysis devices, wound dressings, adhesives, pacemaker, tissue engineering, and coatings for breast implants due to its mechanical flexibility, high tear strength, biocompatibility, and tailorable foams although bio-acceptability, biodegradability and controlled drug delivery to achieve the desired properties should be considered. Especially, during the last decade, the development of bio-based PUs has raised public awareness because of the concern with global plastic waste for creating more environmentally friended materials. Therefore, it is desirable to discuss polysaccharide (PS)-contained PU for the wound dressing and bone tissue engineering among biobased PUs because PS has several advantages, such as biocompatibility, reproducibility from the natural resources, degradability, ease of incorporation of bioactive agents, ease of availability and cost-effectiveness, and structural feature of chemical modification to meet the desired needs to overcome the disadvantages of PU itself by containing the PS into the PU.
