Analysis of Factors Affecting Local Recurrences after Thyroid Surgery in Low Risk Papillary Thyroid Carcinomas.
10.16956/kjes.2008.8.2.118
- Author:
Seung Woo LIM
1
;
Sung Jin PARK
;
Hyunjin CHO
;
Geumhee GWAK
;
Keun Ho YANG
;
Byung Noe BAE
;
Ki Whan KIM
;
Hong Joo KIM
;
Young Duck KIM
;
Sehwan HAN
Author Information
1. Department of Surgery, Sanggye Paik Hospital, College of Medicine, Inje University, Seoul, Korea. hanse@paik.ac.kr
- Publication Type:Original Article
- Keywords:
AGES;
Local recurrence;
Papillary thyroid carcinoma;
Thyroidectomy
- MeSH:
Carcinoma, Papillary;
Classification;
Female;
Humans;
Iodine;
Lymph Nodes;
Neck;
Neoplasm Metastasis;
Recurrence*;
Thyroglobulin;
Thyroid Gland*;
Thyroid Neoplasms*;
Thyroidectomy
- From:Korean Journal of Endocrine Surgery
2008;8(2):118-122
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study analyzed factors affecting local recurrences in AGES low risk papillary thyroid carcinomas (PTCs). METHODS: The clinical records of 89 patients who underwent thyroidectomy because of PTC were reviewed. Seventy patients had belonged to low risk PTC according to the AGES classification scheme. The clinical data of these patients concerning disease recurrence was analyzed considering age, gender, operative methods, tumor size, lymph node (LN) metastasis, postoperative radioactive iodine scan (RI scan ¹³¹I), and Synthyroid® intake. RESULTS: Of the 70 patients, 56 were female (80%). Thirtyseven patients underwent total thyroidectomy with central neck LN dissection and 33 patients underwent partial thyroidectomy with ipsilateral central neck LN dissection. Mean tumor size was 2 cm (0.4~6 cm) and 31 patients had LN metastasis. Levels were <1µg/L in all patients who underwent total thyroidectomy but were 1~10µg/L in patients who received partial thyroidectomy thyroglobulin. Local recurrencein AGES low risk papillary carcinomas was significantly associated with tumor size >2 cm (P=0.030) and partial thyroidectomy (P=0.045). There was no significant association between local recurrence and age, gender, extrathyroidal extension, LN metastasis, RI scan ¹³¹I, or Synthyroid® intake. CONCLUSION: Partial thyroidectomy and tumor size >2 cm are significantly associated with local recurrence in AGES low risk papillary thyroid carcinomas.
