Three Cases of SARS-CoV-2 Infection with Cold Antibody of Undetermined Specificity in Antibody Screening in Transfusion Labs
10.17945/kjbt.2022.33.2.1 0 7
- Author:
Beom Joon KIM
1
;
Dong Woo SHIN
;
Yun Ji HONG
;
Hyungsuk KIM
;
Kyoung Un PARK
Author Information
1. Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
- Publication Type:Case Report
- From:Korean Journal of Blood Transfusion
2022;33(2):107-113
- CountryRepublic of Korea
- Language:English
-
Abstract:
SARS-CoV-2 infections continue to occur in this worldwide pandemic and have been associated with various symptoms, including autoimmune disorders. Of the latter, several reports of SARS-CoV-2-associated cold-agglutinin syndrome (CAS) have been published. CAS is associated with other viral infections, such as that by the Epstein–Barr virus. This paper reports a case series of SARS-CoV-2-associated cold-agglutinin syndrome presenting as an antibody of undetermined specificity mainly reactive at cold temperatures and mostly detected as C3d, but sometimes as IgM on the direct antiglobulin test.
