A Case of IgG4-Related Pseudotumor in Larynx
10.22469/jkslp.2022.33.2.110
- Author:
Min Hyuk LEE
1
;
Joon Pyo HONG
;
Tae Hwan KIM
;
Sung Min JIN
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
- Publication Type:Case Report
- From:Journal of the Korean Society of Laryngology Phoniatrics and Logopedics
2022;33(2):110-114
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
IgG4-related disease is a fibroinflammatory condition by infiltration of IgG4-positive plasma cells that often presents as a tumorous lesion. This disease can affect nearly every organ system. After the pancreas, the head and neck region is second most common site for presentation of IgG4- related disease such as Mikulicz’s disease, Küttner tumor. The involvement of IgG4-related disease in laryngeal lesions is extremely rare. We have experienced a case of IgG4-related disease with pseudotumor formation in the larynx that is suggestive of malignancy in radiologic findings. But the pathology findings was finally confirmed as IgG4-related disease. Oral treatment with prednisolone was initiated, and the edematous mass reduced in size without permanent functional impairment of vocal fold mobility. We report our experience with a literature review.