Korean Medication Algorithm Project for Bipolar Disorder 2022: Maintenance Therapy
10.4306/jknpa.2022.61.3.214
- Author:
Jung Goo LEE
1
;
Won-Myong BAHK
;
Young Sup WOO
;
Jong-Hyun JEONG
;
Jeong Seok SEO
;
IL Han CHOO
;
Chan-Mo YANG
;
Won KIM
;
Se-Hoon SHIM
;
Myung Hun JUNG
;
Duk-In JON
;
Sung-Yong PARK
;
InKi SOHN
;
Moon-Doo KIM
;
Bo-Hyun YOON
Author Information
1. Department of Psychiatry, Haeundae Paik Hospital, College of Medicine, Inje University, Busan, Korea
- Publication Type:ORIGINAL ARTICLE
- From:Journal of Korean Neuropsychiatric Association
2022;61(3):214-223
- CountryRepublic of Korea
- Language:English
-
Abstract:
Objectives:In this study, we investigated and organized the maintenance-treatment strategies for Bipolar I and II disorders outlined in The Korean Medication Algorithm Project for Bipolar disorder 2022 (KMAP-BP 2022).
Methods:The questionnaire sought to survey expert opinion on medication for bipolar disorders and was completed by a review committee consisting of 87 experienced Korean psychiatrists. It comprised 56 questions, and each question included various sub-items. The questionnaire for the maintenance treatments covered overall treatment strategies after acute mood episodes in bipolar I and II disorders, the choice of mood stabilizers and atypical antipsychotics and antidepressants, duration of medication, and treatment strategies for breakthrough symptoms.
Results:In the case of bipolar I disorder, mood stabilizer monotherapy, atypical antipsychotics monotherapy, and a combination of mood stabilizers and atypical antipsychotics were selected as the first-line treatments. In maintenance management of bipolar II disorder, mood stabilizer monotherapy, atypical antipsychotics monotherapy, and combinations of mood stabilizers were selected as the preferred first-line treatments.
Conclusion:There has been a growing body of evidence that atypical antipsychotics have a greater preference than observed in the previous KMAP-BP of 2018. Also, monotherapy of mood stabilizers or atypical antipsychotics was more frequently selected in KMAP-BP 2022 than in the KMAP-BP 2018.
