Lung Cancer Screening: Subsequent Evidences of National Lung Screening Trial.
- Author:
Young Sik PARK
1
Author Information
- Publication Type:Review
- Keywords: Lung Neoplasms; Early Detection of Cancer; Tomography, X-Ray Computed; Thorax
- MeSH: Bias (Epidemiology); Diagnosis; Early Detection of Cancer; Humans; Lung Neoplasms*; Lung*; Mass Screening*; Mortality; Thorax; Tomography, X-Ray Computed
- From:Tuberculosis and Respiratory Diseases 2014;77(2):55-59
- CountryRepublic of Korea
- Language:English
- Abstract: The US National Lung Screening Trial (NLST) demonstrated a 20% reduction in lung cancer mortality and a 6.7% decrease in all-cause mortality. The NLST is the only trial showing positive results in a high-risk population, such as in patients with old age and heavy ever smokers. Lung cancer screening using a low-dose chest computed tomography might be beneficial for the high-risk group. However, there may also be potential adverse outcomes in terms of over diagnosis, bias and cost-effectiveness. Until now, lung cancer screening remains controversial. In this review, we wish to discuss the evolution of lung cancer screening and summarize existing evidences and recommendations.
