A Case of Venlafaxine-Induced Interstitial Lung Disease.
- Author:
Serim OH
1
;
Seung Ick CHA
;
Hyera KIM
;
Minjung KIM
;
Sun Ha CHOI
;
Hyewon SEO
;
Tae In PARK
Author Information
- Publication Type:Case Report
- Keywords: Hypersensitivity; Pneumonia; Lung Disease, Interstitial; Venlafaxine
- MeSH: Alveolitis, Extrinsic Allergic; Bronchiectasis; Depression; Glass; Humans; Hypersensitivity; Lung; Lung Diseases, Interstitial*; Perfusion; Pneumonia; Traction; Venlafaxine Hydrochloride
- From:Tuberculosis and Respiratory Diseases 2014;77(2):81-84
- CountryRepublic of Korea
- Language:English
- Abstract: A patient treated with venlafaxine for major depression developed an interstitial lung disease (ILD) with the characteristic clinical, radiological and pathological features of chronic hypersensitivity pneumonitis. A high resolution computed tomography scan demonstrated ground glass opacity, mosaic perfusion with air-trapping and traction bronchiectasis in both lungs. The pathological findings were consistent with a nonspecific interstitial pneumonia pattern. Clinical and radiological improvements were noted after the discontinuation of venlafaxine and the administration of a corticosteroid. This report provides further evidence that the anti-depressant venlafaxine can cause ILD.
