A case of mantle cell lymphoma associated with tuberculous pleurisy.
- Author:
Hynu Su LEE
1
;
Soo Keol LEE
;
Kwang Yul CHANG
;
Ik Soo CHOI
;
Choon Hee SON
;
Jae Seok KIM
;
Jin Sook JEON
;
Mee Sook RHO
;
Jin Yeong HAN
;
Ki Nam LEE
;
Pil Jo CHOI
Author Information
1. Department of Internal Medicine, Dong-A University College of Medicine, Pusan, Korea.
- Publication Type:Case Report
- Keywords:
Mantle cell lymphoma;
Pleurisy;
Tuberculous
- MeSH:
Biopsy;
Drug Therapy;
Dyspnea;
Female;
Flow Cytometry;
Hepatitis;
Humans;
Inflammation;
Liver Failure;
Lymphoma;
Lymphoma, Mantle-Cell*;
Middle Aged;
Pleural Effusion;
Pleurisy;
Thorax;
Tuberculosis;
Tuberculosis, Pleural*
- From:Korean Journal of Medicine
2002;62(4):469-474
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Mantle cell lymphoma is relatively rare and generally difficult to differentiate from other types of lymphoma. The clinical course is very aggressive. We recently experienced a very rare patient with pleural mantle cell lymphoma associated with pleural tuberculosis. A 60-year-old female patient was admitted because of dyspnea. Chest films revealed pleural effusion. Analysis of pleural effusion was not diagnostic, but we started therapeutic trial for tuberculosis. After 2 months of anti-tuberculosis medication, the pleural effusion was not improved. We repeated pleural biopsy. Histologic finding was chronic inflammation but AFB culture was positive. After another 3 months of medications for tuberculosis, there was no improvement. We repeated pleural biopsy and thoracentesis. Repeated biopsy and the result of flow cytometry of pleural effusion were consistent with mantle cell lymphoma. We started chemotherapy for lymphoma. After three cycles of chemotherapy, pleural effusion was decreased, but she worsened and died of hepatic failure probably due to viral hepatitis.
