A Transient Effect of Convalescent Plasma Therapy in a Patient with Severe Covonavirus Disease 2019: A Case Report
- Author:
Ae-Rin BAEK
1
;
Eun Ju CHOO
;
Ji-Yeon KIM
;
Tae Sun HA
;
Sung Woo PARK
;
Hee Bong SHIN
;
Seong Kyu PARK
;
Joo Hyun PARK
;
Tark KIM
Author Information
- Publication Type:Case Report
- From:Infection and Chemotherapy 2022;54(3):553-558
- CountryRepublic of Korea
- Language:English
- Abstract: A 65-year-old male patient with an end-stage renal disease was diagnosed with coronavirus disease 2019 (COVID-19) by reverse transcription polymerase chain reaction. The patient complained of cough, sputum, and respiratory distress that worsened three days ago. The patient required mechanical ventilation and extracorporeal mentrane oxygenation. On day 9, convalescent plasma collected from a 34-year old man who recovered from COVID-19 45 days ago was administered. The patient showed immediate clinical improvement. However, on day 14, the patient’s clinical course worsened again. On day 19 and day 24, vancomycin-resistant Enterococcus faecium bacteremia and methicillin-resistant Staphylococcus aureus pneumonia were found. After long-term supportive care, he slowly recovered. He was discharged on day 91 without any oxygen requirement. This case report suggests that convalescent plasma therapy might just provide a short-term relief and that persistent effort for critical care is necessary to save patients from severe COVID-19.
