Clinical Significance of Total Colonoscopy in Patients with Active Pulmonary Tuberculosis without Gastrointestinal Symptoms.
- Author:
Dong Kyu PARK
1
;
Jae Hong PARK
;
Young Sun KIM
;
Yong Leul OH
;
Chul Hee PARK
;
Yoon Tae JEEN
;
Hong Sik LEE
;
Hoon Jai CHUN
;
Sang Woo LEE
;
Soon Ho UM
;
Jai Hyun CHOI
;
Chang Duck KIM
;
Ho Sang RYU
;
Jin Hai HYUN
Author Information
1. Department of Internal Medicine,Korea University College of Medicine, Seoul, Korea. kumccjh@ns.kumc.or.kr
- Publication Type:Original Article
- Keywords:
Asymptomatic intestinal tuberculosis;
Early lesion;
Total colonoscopy
- MeSH:
Axis, Cervical Vertebra;
Cecum;
Colon;
Colonoscopy*;
Drug Therapy;
Follow-Up Studies;
Humans;
Hyperemia;
Ileum;
Incidence;
Mass Screening;
Mucous Membrane;
Prevalence;
Prospective Studies;
Thorax;
Tuberculosis;
Tuberculosis, Pulmonary*;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
2002;24(4):193-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Pulmonary tuberculosis may coexist with intestinal tuberculosis even in the absence of gastrointestinal symptoms. The aim of this prospective study was to define the colonoscopic findings of early lesions of intestinal tuberculosis, incidence of asymptomatic intestinal tuberculosis in patients with active pulmonary tuberculosis and to evaluate the clinical response after standard anti- tuberculosis chemotherapy. METHODS: We examined 59 Korean patients with active pulmonary tuberculosis, who had no gastrointestinal symptoms. Patients underwent diagnostic total colonoscopy up to terminal ileum for evaluation of intestinal tuberculosis. Follow-up total colonoscopy was also done in 1~3 months after start of treatment. RESULTS: Intestinal tuberculous lesions were found in 54% of patients. The common locations of lesion were terminal ileum (84%) and cecum (69%). The combination of circumferential ulceration, hyperemic mucosa and erosions of the colon was the most common finding (37.5%), the combination of hyperemia and ulceration occurred in 34.4% of patients and hyperemia with/without erosion in 12.5%. The direction of ulceration was transevere in relation to long axis of the colon but occasionally longitudinal. Although most ulcers were multiple in number and various in size but some paitents had isolated single ulcer with erosion. All of the lesions regressed within 1~3 months of treatment. CONCLUSIONS: During screening total colonoscopy, if there are nonspecific hyperemia, erosion or shallow ulcer on colon or terminal ileum, it is necessary to check up chest X-ray for rule out tuberculous lesion, especially in countries with a high prevalence of tuberculosis.
