Clinicopathological Study on Laterally Spreading Tumor (LST).
- Author:
Yeum Seok LEE
1
;
Seon Mun KIM
;
Hyeon Woong YANG
;
Seung Weon SEO
;
Jae Kyu SEONG
;
Byoung Kyu NA
;
Byung Seok LEE
;
Hyun Yong JEONG
Author Information
1. Department of Internal Medicine, Chung Nam National University College of Medicine, Daejeon, Korea. jeonghy@cnuh.co.kr
- Publication Type:Original Article
- Keywords:
LST;
Malignant change;
Submucosal invasion;
Invasion depth;
Endoscopic Mucosal Resction
- MeSH:
Colon;
Colonoscopy;
Female;
Humans;
Male;
Polyps;
Ultrasonography
- From:Korean Journal of Gastrointestinal Endoscopy
2002;24(4):206-211
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Laterally spreading tumors (LST) were growthed along the colonic wall. These tumors were high malignant potential compared to colon polyp. We analyzed clinicopathological characteristics of these tumors. METHODS: From June 1996 to June 2001, twenty nine patients were diagnosed by colonoscopy. These lesions were classificated macroscopic (granular type and nongranular type) and microscopic findings. RESULTS: 20 male and 9 female were enrolled (mean age, 68.1). Among the LST, 41.4% were 20~30 mm in diameter, and 7% were larger than 30 mm. According to macroscopic findings granular types were 72.4% (21/29) and nongranular types were 27.6% (8/29). In macroscopic findings, tubular types were 48.4% (14/29), malignant changes were 31.3% (9/29). Tumor size was only significant factor in malignant potential of LST (p=0.004). Endoscopic mucosal resection was performed in 72.4% (21/29), operation in 8 (27.6%). Rate of submucosal invasion in LST was 3.4% (1/29, sm1). Recurrent rate of endoscopic treatment group was 9.5% (2/21). CONCLUSIONS: Most of LST were good indication for endoscopic treatment, but larger tumor size and irregular surface of tumor were suspected to be submucosal invasion. Therefore these lesions were performed other procedures as endoscopic ultrasound or computerized tomography for invasion depth.
