Correlation Between Frequency Doubling Technology Perimetry and Scanning Laser Polarimetry in Glaucoma Suspects and Glaucomatous Eyes.
- Author:
Su Hyun KIM
1
;
Hunei HONG
;
Hee Jo KOO
;
Sung jae YANG
;
Hungwon TCHAH
;
Michael S KOOK
Author Information
- Publication Type:Original Article ; Comparative Study
- Keywords: frequency doubling technology perimetry (FDT); glaucoma; glaucoma suspects; retinal nerve fiber layer (RNFL); scanning laser polarimetry (SLP)
- MeSH: Comparative Study; Glaucoma, Open-Angle/*diagnosis/physiopathology; Humans; Intraocular Pressure; Lasers/diagnostic use; Microscopy, Confocal; Middle Aged; Nerve Fibers/*pathology; Ocular Hypertension/diagnosis/physiopathology; Optic Nerve/*pathology; Perimetry/*methods; Retinal Ganglion Cells/*pathology
- From:Korean Journal of Ophthalmology 2004;18(2):89-99
- CountryRepublic of Korea
- Language:English
- Abstract: The aim of this study was to determine the relationship between the frequency doubling technology (FDT) screening algorithm and parapapillary retinal nerve fiber layer (RNFL) thickness in the eyes of glaucoma suspects and patients with open angle glaucoma. FDT C20-1 screening program and a scanning laser polarimetry (SLP) system (GDx-NFA) was used to assess 53 glaucomatous eyes, 53 glaucoma suspects and 36 normal control eyes. In glaucomatous eyes, there were correlations between the FDT the screening algorithm and RNFL retardation values in several polarimetric indices, most significantly "inferior thickness" (r = -0.321, P = 0.029). In the eyes of glaucoma suspects, however, we observed no correlation between the FDT results and RNFL retardation values (r = 0.080, P > 0.05, "inferior thickness"). In glaucomatous eyes, the abnormal scores obtained with FDT screening program correlated negatively with RNFL retardation values, as measured by SLP. Despite poor correlation between the FDT abnormal score and RNFL retardation value in glaucoma suspects, detection of abnormality using the FDT screening protocol may aid in the assessment of early glaucomatous structural damage.
