Effects of Mild Hypothermia Hemofiltration on Cerebral Blood Flow in Severe Brain Injuries

VernacularTitle:亚低温血液滤过对重症脑损伤脑血流动力学的影响
Author: Dan LIU ; Hong DING ; Yanyan XU
Publication Type:Journal Article
Keywords: hemofiltration, mild hypothermia, severe traumatic brain injury, cerebral blood flow, intracranial pressure
From: Chinese Journal of Rehabilitation Theory and Practice 2012;18(2):111-113
CountryChina
Language:Chinese
Abstract: Objective To observe the effects of mild hypothermia hemofiltration on cerebral blood flow (CBF) and intracranial pressures (ICP) in patients with severe brain injury. Methods 65 patients with severe brain injuries were divided into control group (n=30) and observation group (n=35). The control group accepted the routine treatment only while the observation group accepted mild hypothermia hemofiltration additionally. CBF was detected by Transcranial Doppler (TCD) and ICP was monitored by ICP monitor. Glasgow Coma Scale (GCS) was assessed every day. Results 5 d after treatment, the scores of GCS were higher in the observation group than in the control group (P<0.05) as well as the CBF (P<0.05), but the ICP was in the observation group significantly lower than in the control group (P<0.01). Conclusion Compared with the traditional mild hypothermia, mild hypothermia hemofiltration can improve hemodynamic changes caused by severe brain injury, reduce ICP and improve the outcomes.