Effect of Mouse Nerve Growth Factor on Neural Function of Patients after Operation for Protrusion of the Lumbar Intervertebral Disc

VernacularTitle:鼠神经生长因子对腰椎间盘突出患者术后神经恢复的作用
Author: Kaifang ZHANG ; Zhongwei GUO ; Huanjin SONG
Publication Type:Journal Article
Keywords: protrusion of the lumbar intervertebral disc, mouse nerve growth factor, posterior lamina resection nucleus pulposus decompressionexcise pedicle screws fixation, pain, electromyogram
From: Chinese Journal of Rehabilitation Theory and Practice 2012;18(1):84-86
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of mouse nerve growth factor on protrusion of the lumbar intervertebral disc (LDP) treated with operation. Methods 60 cases with LDP received posterior lamina resection nucleus pulposus decompression excise pedicle screws fixation, in which 30 cases (the treatment group) accepted mouse nerve growth factor for 30 d. Their symptoms and signs, visual analogue score (VAS) for pain, and the electromyogram were recorded before and after treatment. Results The VAS in the treatment group improved more than in control group (P<0.05). the incidence of cure and improvement (76.7%) was higher than in the control group (50.0%)(P<0.05). The nerve conduction velocity and action potential of main muscle group also improved more in the treatment group (P<0.05).Conclusion Mouse nerve growth factor can improve the recovery of pain as well as the neural function in patients after operation for LDP.