Brain functioning between dominant and non-dominant hemispheres during rehabilitation for subacute stroke
10.3969/j.issn.1006-9771.2022.11.014
- VernacularTitle:亚急性脑卒中患者康复过程中优势与非优势脑半球功能变化差异
- Author:
Chaojinzi LI
1
;
Fubiao HUANG
1
;
Xiaoxia DU
1
;
Haojie ZHANG
1
;
Tong ZHANG
1
Author Information
1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
- Publication Type:Journal Article
- Keywords:
stroke;
subacute;
upper limb;
dominant hemisphere;
functional near-infrared spectroscopy;
brain plasticity
- From:
Chinese Journal of Rehabilitation Theory and Practice
2022;28(11):1342-1348
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe the differences of brain functioning between dominant and non-dominant hemispheres during rehabilitation for subacute stroke based on functional near-infrared spectroscopy (fNIRS). MethodsFrom September, 2019 to June, 2020, ten subacute stroke inpatients with left hemiplegia (non-dominant hemisphere group) and 16 with right hemiplegia (dominant hemisphere group) from Beijing Bo'ai Hospital received the same unilateral task-oriented occupational therapy for upper limbs, for four weeks. They were assessed with Action Research Arm Test, Fugl-Meyer Assessment-Upper Extremities and grip strength before and after treatment, and scanned with fNIRS to the β value of bilateral sensorimotor cortex, premotor cortex and prefrontal cortex according to the changes of oxyhemoglobin concentration. ResultsAll the indexes of assessment improved in the both groups after treatment (|t| > 3.253, P < 0.05), while the scores of Action Research Arm Test and grip strength improved more in the dominant hemisphere group than in the non-dominant hemisphere group (|t| > 2.154, P < 0.05). For the β value of fNIRS, there was no main effect on time, region and groups (F < 0.542, P > 0.05), and the interactive effect between region and group was significant (F = 4.226, P < 0.01): In the dominant hemisphere group, the β value was higher in the ipsilateral premotor cortex than in the contralateral cortex (P = 0.030), and it was less in the contralateral prefrontal cortex than in the ipsilateral sensorimotor cortex (P = 0.024), ipsilateral premotor cortex (P = 0.003) and ipsilateral prefrontal cortex (P = 0.018). ConclusionFor the subacute stroke patients with right hemiplegia, the activation of brain regions is different between dominant and non-dominant hemispheres during the rehabilitation of upper limb and hand.
