Effect of Botulinum Toxin-A on Spastic Iliopsoas in Children with Cerebral Palsy
10.3969/j.issn.1006-9771.2013.10.015
- VernacularTitle:A型肉毒毒素对脑性瘫痪患儿髂腰肌痉挛的疗效观察
- Author:
Jianjun LIU
;
Shurong JI
;
Weihong WU
;
Yan ZHANG
;
Zengyong ZENG
;
Nanling LI
- Publication Type:Journal Article
- Keywords:
cerebral palsy, spasticity, Botulinum toxin-A, iliopsoas, gait, gross motor function
- From:
Chinese Journal of Rehabilitation Theory and Practice
2013;19(10):956-959
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Botulinum toxin-A (BTX-A) injection on spastic iliopsoas in the children with cerebral palsy. Methods July 2006 to August 2012, 37 cerebral palsy children with spastic iliopsoas were treated. The age ranged from 3 to 15 years.The control group (n=20) was treated by physical therapy. The experimental group (n=17) accepted BTX-A injection in addition. The dose of BTX-A block was identified with the weight of the child and the modified Ashworth Scale (MAS). The dose of injection ranged from 15 IU to 45 IU, average (31.2±13.9) IU. Results There was no significant difference between 2 groups in age, weight, MAS score, Gross Motor Function Measure (GMFM) score and extension angle of hip joints before treatment (P>0.05). In both groups, the MAS score decreased,GMFM score and extension angle of hip joints increased after 8 weeks. In the control group, the GMFM score improved significantly (P<0.05). In the experimental group, MAS score, GMFM score and extension angle of hip joints changed significantly after treatment. There was significant difference between 2 groups in MAS score, GMFM score and extension angle of hip joints after treatment (P<0.05). Conclusion The BTX-A injection can relieve iliopsoas spasticity on the children with cerebral palsy efficiently.
