Calcium Signaling and Neurodegenerative Diseases (review)
10.3969/j.issn.1006-9771.2013.10.008
- VernacularTitle:钙信号与神经退行性疾病
- Author:
Fangling SUN
;
Wen WANG
;
Xunming JI
;
Xiaomin WANG
;
Lan ZHANG
;
Lin LI
- Publication Type:Journal Article
- Keywords:
neuronal calcium signaling, Alzheimer's disease, Parkinson's disease, aging, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2013;19(10):931-935
- CountryChina
- Language:Chinese
-
Abstract:
Neuronal calcium (Ca2+) signaling is abnormal in neurodegenerative disorders such as Alzheimer's disease (AD), and Parkinson's disease (PD). The increase in neuronal Ca2 + concentration as a result of normal aging could promote the neurodegenerative process.The role of aberrant neuronal Ca2+ signaling in the pathogenesis of neurodegenerative disorders and aging process was discussed here.