Advance in MicroRNA Related with Spinal Cord Injury (review)
10.3969/j.issn.1006-9771.2013.07.011
- VernacularTitle:脊髓损伤相关的microRNA研究进展
- Author:
Jianmin CHEN
;
Zheng YANG
;
Nan LIANG
;
Xiao ZHANG
- Publication Type:Journal Article
- Keywords:
spinal cord injury, microRNA, posttranscriptional gene regulation, neurodegeneration, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2013;19(7):635-639
- CountryChina
- Language:Chinese
-
Abstract:
Spinal cord injury (SCI) is a kind of severe central nervous system trauma causing motion and/or sensation dysfunction. MicroRNAs are short non-coding RNAs that suppress the translation of target genes, and play an important role in gene regulation involved in spinal cord development and SCI, which constitute novel targets for therapeutic intervention to promote repair and regeneration.