Inflammation in Parkinson's Disease (review)
10.3969/j.issn.1006-9771.2013.07.012
- VernacularTitle:炎症在帕金森病中的作用
- Author:
Tingwei YUAN
;
Fangling SUN
;
Ying JIANG
;
Houxi AI
;
Li ZHANG
;
Wen WANG
;
Dachun GONG
- Publication Type:Journal Article
- Keywords:
Parkinson's disease, neuroinflammation, systemic inflammation, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2013;19(7):640-644
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson's disease is a common progressive neurodegenerative disorder among old people, characterized by progressive loss of dopamine-producing neurons in the substantia nigra pars compacta and accordingly low level of dopamine in the nigrostriatal pathway.Neuroinflammation and even systemic inflammation have been suggested to be involved in the demise of dopaminergic neurons. Anti-inflammatory treatment could protect brain from inflammatory injury and prevent the progressive course of Parkinson's disease, which suggests a potential new strategy for Parkinson's disease treatment.
