Palliative effect of (131)I-MIBG in relapsed neuroblastoma after autologous peripheral blood stem cell transplantation.
10.3345/kjp.2008.51.2.214
- Author:
Yong Jik LEE
1
;
Jeong Ok HAH
Author Information
1. Department of Hematology/Oncology, Yeungnam University College of Medicine, Korea. johah@med.yu.ac.kr
- Publication Type:Case Report
- Keywords:
Relapsed neuroblastoma;
(131)I-MIBG;
Palliative therapy
- MeSH:
Neuroblastoma;
Palliative Care;
Peripheral Blood Stem Cell Transplantation
- From:Korean Journal of Pediatrics
2008;51(2):214-218
- CountryRepublic of Korea
- Language:English
-
Abstract:
Neuroblastoma is one of the most common extracranial solid tumor of childhood, and treatment of refractory neuroblastoma remains a significant clinical problem. Iodine-131-metaiodobenzylguanidine ((131)I-MIBG) therapy is an alternative approach to treat stage IV neuroblastoma. We report the palliative effect of (131)I-MIBG in three cases of relapsed neuroblastoma after autologous peripheral blood stem cell transplantation. (131)I-MIBG is an effective and relatively nontoxic palliative therapy resulting in reduction of pain and prolongation of survival.
