Research progress on aluminum load in children and the mechanism of aluminum neurotoxicity
10.16835/j.cnki.1000-9817.2022.11.037
- VernacularTitle:儿童铝负荷状况及铝神经毒作用机制的研究进展
- Author:
PEI Jing, ZHANG Lifeng
1
Author Information
1. Department of Maternal, Child and Adolescent Health, School of Public Health, Shenyang Medical College, Shenyang (110034) , China
- Publication Type:Journal Article
- Keywords:
Aluminum;
Body burden;
Poisoning;
Child
- From:
Chinese Journal of School Health
2022;43(11):1755-1760
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:Aluminum is a chronic and cumulative environmental neurotoxin. Human exposure to aluminum is inevitable and impossible to quantify. The level of aluminum load is on the rise, the neurobiological toxicity of which is a cause for great concern. Aluminum intake, absorption, and load levels in the body are often higher in children in stages of rapid growth and development than in ordinary adults. Long term low dose aluminum load levels may cause a variety of chronic subclinical damage and long term irreversible damage to the neurodevelopmental function of children. Therefore, this review primarily elucidates the status of aluminum load in children and its effect on neurodevelopmental functioning. Furthermore, we examine research progress on the related mechanism of impaired neurodevelopmental functioning so as to provide a theoretical basis for the treatment and prevention of health problems caused by aluminum load in children and outline proposals for healthcare in this area.
