Research progress on genetic variants effects on childhood obesity interventions
10.16835/j.cnki.1000-9817.2022.11.034
- VernacularTitle:基因变异对儿童肥胖干预效果作用的研究进展
- Author:
CHEN Jing, WANG Haijun, WANG Hui, SONG Jieyun, XIAO Wucai, LIU Zheng
1
Author Information
1. Department of Maternal and Child Health, School of Public Health, Peking University, Beijing (100191) , China
- Publication Type:Journal Article
- Keywords:
Genes;
Obesity;
Child;
Intervention
- From:
Chinese Journal of School Health
2022;43(11):1740-1744
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:In recent decades, the prevalence of childhood obesity has increased at a alarming rate. The health hazards of childhood obesity are substantial, which has become an important public health problem. Lifestyle intervention is an effective means to prevent childhood obesity. However, individuals varied in their response to the intervention program, which may be associated with genetic factors. This paper systematically reviews the research progress of the effects of FTO, MC4R and other genetic variants on childhood obesity interventions, summarizes the limitations of current research and sheds light on the future research, so as to provide scientific evidence for individualized childhood obesity interventions based on genetic backgrounds.
