Infection status and molecular characteristics of Campylobacter isolated from diarrhea patients in Changping District of Beijing
10.3969/j.issn.1006-2483.2022.06.029
- VernacularTitle:北京市昌平区腹泻患者弯曲菌感染现状及其分子特征分析
- Author:
Dong-xun LI
1
;
Wei-jun WANG
1
;
Hua PENG
1
;
An-qi YIN
1
;
Gao-lin SHU
1
;
Heng-cai LIU
1
Author Information
1. Department of Microbiology , Changping District Center for Disease Control and Prevention , Changping , Beijing 102200 , China
- Publication Type:Journal Article
- Keywords:
Diarrhea patients;
Campylobacter;
Campylobacter jejuni;
Campylobacter coli;
Pulsed-field gel electrophoresis
- From:
Journal of Public Health and Preventive Medicine
2022;33(6):123-127
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the infection status and molecular characteristics of Campylobacter, and to provide evidence for the prevention and control of Campylobacter infection. Methods A total of 382 stool samples from diarrhea patients in a sentinel hospital in Changping District, Beijing, were collected in 2019. Campylobacter, Salmonella, Diarrhea Escherichia coli, and Vibrio Parahaemolyticus were detected, and the isolated Campylobacter jejuni strains were analyzed by pulsed-field gel electrophoresis (PFGE). Results The positive detection rate of Campylobacter (58 strains, 15.18%) was higher than that of Diarrhea Escherichia coli (37 strains, 9.69%), Salmonella (24 strains, 6.28%) and Vibrio Parahaemolyticus (21 strains, 5.50%), and the difference was statistically significant (χ2=26.735, P=0.000). Campylobacter strains were found in spring (14.71%), summer (18.33%), autumn (15.00%) and winter (10.00%), but there was no significant difference (χ2=2.197, P=0.533). PFGE analysis showed that 30 strains of Campylobacter jejuni had 26 PFGE patterns, and the similarity coefficient was 31.00% -100.00%. Conclusion In the study, the detection rate of Campylobacter is in the first place, and it is detected in four seasons, indicating that the infection of Campylobacter is serious in Changping District of Beijing. It is necessary to pay more attention to the infection of Campylobacter and formulate corresponding policies to prevent the outbreak caused by Campylobacter infection..
