Logistic regression analysis of risk factors related to severe imported falciparum malaria
10.3969/j.issn.1006-2483.2022.06.017
- VernacularTitle:输入性恶性疟疾重症相关危险因素logistic回归分析
- Author:
Shuang WU
1
;
Dan-ning WEN
1
;
Shu-kun YU
2
;
Shu PAN
1
;
Dan XIE
1
;
Ke-jiao LONG
1
;
Chong FU
1
;
Han-dan ZHENG
1
;
Dan LUO
1
;
Hua-dong LI
1
Author Information
1. Wuhan Jinyintan Hospital , Wuhan , Hubei 430023 , China
2. Dongxihu District Center for Disease Control and Prevention , Wuhan , Hubei 430040 , China
- Publication Type:Journal Article
- Keywords:
Falciparum malaria;
Severe disease;
Risk factors;
Logistic regression analysis
- From:
Journal of Public Health and Preventive Medicine
2022;33(6):72-75
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore and analyze the risk factors of severe falciparum malaria cases,and to provide evidence for early clinical prevention and intervention measures. Methods A total of 114 imported cases of falciparum malaria in Wuhan from March 2012 to November 2019 were selected,divided into mild group(n=87)and severe group(n=27),and logistic regression analysis was performed on the risk factors of severe disease. Results There were significant differences in length of stay, erythrocyte, hemoglobin, platelet, urea, creatinine, albumin, creatine kinase isoenzyme, lactate dehydrogenase, urine occulting blood and urine protein between mild group and severe group (P<0.05).Multivariate Logistic regression analysis showed that alanine aminotransferase (OR=0.167, 95%CI: 0.042-0.668), albumin (OR=24.843, 95% CI: 5.170-119.383), urea (OR=0.240,95%CI: 0.074-0.779) and occulted blood in urine (OR=0.204, 95%CI: 0.062-0.672) were independent influencing factors for the occurrence of severe falciparum malaria. Conclusion Patients with liver function damage and alanine aminotransferase increased by more than 2 times(≥80U/L),albumin decreased(<30g/L),renal function damage,increased urea nitrogen,hematuria and other abnormal results, the possibility of severe falsiparum malaria development should be highly suspected.
