Current research status and prospect of circulating tumor DNA in hepatocellular carcinoma
10.3969/j.issn.1001-5256.2022.11.036
- VernacularTitle:循环肿瘤DNA在肝细胞癌中的研究现状及展望
- Author:
Zhiyuan HOU
1
;
Yuan LIU
1
;
Chaoran YANG
1
;
Jisen ZHAO
1
;
Shujie CHENG
1
Author Information
1. Department of Hepatobiliary Surgery, Affiliated Hospital of Hebei University, Baoding, Hebei 071000, China
- Publication Type:Reviews
- Keywords:
Carcinoma, Hepatocellular;
Neoplastic Cells, Circulating;
DNA
- From:
Journal of Clinical Hepatology
2022;38(11):2616-2620
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world, with the features of insidious onset, low surgical resection rate, and frequent early metastasis and recurrence. With the development of new molecular biology technology in recent years, a liquid biopsy technology, circulating tumor DNA (ctDNA) detection, has achieved encouraging results. This article reviews the current research status and future prospects of ctDNA as a key component of liquid biopsy in patients with HCC, in order to provide new ideas for the clinical treatment of HCC.
