Two Cases of Neonatal Lupus Erythematosus.
- Author:
In Ho KWON
1
;
Jong Yeop YOO
;
Jong Hee LEE
;
Kwang Hyun CHO
Author Information
1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. khcho@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Neonatal lupus erythematosus;
Anti-Ro/SSA anibody
- MeSH:
Antibodies;
Antibodies, Antinuclear;
Autoantibodies;
Female;
Heart Block;
Humans;
Infant;
Lupus Erythematosus, Cutaneous;
Lupus Erythematosus, Systemic;
Male;
Mothers
- From:Korean Journal of Dermatology
2003;41(7):956-959
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neonatal lupus erytematosus is characterized by cutaneous findings showing the morphology of subacute cutaneous lupus erythematosus, congenital heart block, and anti-Ro/SSA and/or anti-La/SSB autoantibodies which result from the transplacental passage of maternal autoantibodies. We report two cases of a 25-day-old female infant and a 30-day-old male infant who presented with characteristic clinical features of cutaneous neonatal lupus erythematosus but without evidence of congenital heart block. The serological studies in both infants revealed the presence of anti-SSA/Ro antibodies and antinuclear antibodies. We diagnosed their mothers as systemic lupus erythematosus with the clinical and laboratory findings.
