Pattern of Inhalant and Food Allergens in Patients with Allergic Rhinitis By Gender in Guangzhou
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2022.0102
- VernacularTitle:广州地区不同性别变应性鼻炎吸入性及食入性变应原谱特征分析
- Author:
Wei-hao WANG
1
;
Wei-feng KONG
1
;
Rui ZHENG
1
;
Yu-lian CHEN
1
;
Qin-tai YANG
1
;
Xue-kun HUANG
1
Author Information
1. Department of Otolaryngology， The Third Hospital of SunYat-sen University， Guangzhou 510630， China
- Publication Type:Journal Article
- Keywords:
allergic rhinitis;
serum specific IgE;
inhalant allergens;
food allergens;
gender
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2022;43(1):10-17
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo analyze the characteristics of the pattern of inhalant and food allergens in patients with allergic rhinitis （AR） by gender in Guangzhou. MethodsBy collecting the results of serum allergen specific IgE （sIgE） test of 7 284 suspected AR patients visiting the ENT outpatient in the Third Hospital of SunYat-sen University from 2016 to 2020. The characteristics of the pattern of inhalant and food allergens in definite AR patients， especially the gender difference in allergen pattern， was compared. ResultsA total of 5 980 patients were confirmed as AR with a 82.10% positive rate （95%CI=81.22%， 82.98%） in allergen serum sIgE test. The mean age of male patients was 19.01±13.17 vs. 23.67±13.40 in female. The mean age of female patients was older than that of the male patients （P<0.001）. Compared with the female patients， the positive rate was higher in the male AR patients （83.35% vs. 80.61%， P<0.05）. The common inhalant allergens in Guangzhou were house dust mites （78.93%）， house dust （17.71%） and mold groups （17.16%）， and milk （20.45%）， cashew nut （20.35%） and crab （18.28%） were the common food allergens. The positive rates of house dust mites and dog dander were higher in males than those in females （all of P<0.05）， while the positive rate of mold groups was higher in females than that in males （P<0.001）. The positive rates of egg， milk， shrimp， beef， crab and cashew nut were higher in male patients than those of the female patients （all of P<0.05）. In minor group， the positive rate of inhalant allergen serum sIgE was higher in males （93.25%） than that in females （90.25%， P<0.05）， while the positive rate of food allergen serum sIgE was higher in adult male patients （54.66%） than that in the adult female patients （49.23%， P=0.002）. ConclusionsThere exist significant difference by gender in the positive rates of allergen among house dust mites， mold groups， dog dander， egg， milk， shrimp， beef， crab and cashew nut. Adult male AR patients seem to be more vulnerable to suffering from food allergy， suggesting the importance of the precise management for AR patients involving the gender characteristics.
