Predictive Value of Hypodensities and Spot Sign for Hematoma Enlargement in Early Stage of Spontaneous Cerebral Hemorrhage
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.2022.0318
- VernacularTitle:低密度征和斑点征预测自发性脑出血早期血肿扩大
- Author:
Shan-shan NIU
1
;
Li-ping ZHONG
1
;
Teng-fei SONG
1
;
Pei-xin QIN
1
;
Ling-mei CHEN
2
;
Ya-qin ZHANG
1
Author Information
1. Department of Diagnostic Radiology，The Fifth Affiliated Hospital of Sun Yat-sen University，Zhuhai 519000， China
2. School of Mathematics， Sun Yat-sen University， Guangzhou 510275， China
- Publication Type:Journal Article
- Keywords:
spontaneous cerebral hemorrhage;
hematoma expansion;
hypodensities;
spot sign
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2022;43(3):496-503
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo explore the application of hypodensities on computed tomography （CT） and the spot sign on CT angiography （CTA） in predicting hematoma expansion in patients with acute intracerebral hemorrhage. MethodsA total of 232 patients with acute intracerebral hemorrhage were retrospectively analyzed. All the patients were divided into hematoma expansion group （62） and hematoma non-expansion group （170）. All patients were examined with CT and CT angiography within 24 hours after onset to determine the volume，and reexamined with CT to determine whether hematoma expansion occurred. General clinical and imaging data of all patients were collected. Univariate survival analysis， Logistic regression analysis and ROC curve were carried out to compare the diagnostic value of hypodensities on CT and the spot sign on CTA in predicting hematoma expansion in patients with acute intracerebral hemorrhage. ResultsUnivariate survival analysis showed the GCS score， initial CT time， spot sign and hypodensities were significantly different between the two groups （P values are 0.003， 0.012， ＜0.001， 0.001， respectively）. Logistic regression analysis showed the initial CT time， spot sign and hypodensities were significantly different between the two groups （P＜0.05）. The area under ROC curve of spot sign， hypodensities， spot sign combined with hypodensities were respectively 0.669， 0.606， 0.726； The sensitivity and specificity of spot sign， hypodensities， spot sign combined with hypodensities were 41.9% and 91.8%， 93.5% and 27.6%， 95.2% and 27.6%， respectively. ConclusionsThe spot sign and hypodensities are independent risk factors for hematoma enlargement. The hypodensities shows a higher sensitivity， the spot sign shows a higher specificity， and the prediction ability of spot sign combined with hypodensities is better than that of alternatively single sign.
