Clinical implications of first CD4+T cell counts among newly reported HIV-infected Burmese in Dehong Prefecture of Yunnan Province in 2019 and 2020

Yanfen Cao; Shuxian HE; Lifen Xiang; Jie Gao; Yuecheng Yang; Renhai Tang; Runhua YE; Jibao Wang; Na HE; Yingying Ding; Song Duan

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Clinical implications of first CD4+T cell counts among newly reported HIV-infected Burmese in Dehong Prefecture of Yunnan Province in 2019 and 2020

VernacularTitle:2019—2020年云南德宏傣族景颇族自治州境内新报告缅甸籍HIV感染者首次CD4+T淋巴细胞计数的临床意义
Author: Yanfen CAO ¹ ; Shuxian HE ² ; Lifen XIANG ¹ ; Jie GAO ¹ ; Yuecheng YANG ¹ ; Renhai TANG ¹ ; Runhua YE ¹ ; Jibao WANG ¹ ; Na HE ² ; Yingying DING ² ; Song DUAN ¹
Author Information

1. Department of STD and AIDS Prevention， Dehong Dai and Jingpo Autonomous Prefecture Center for Disease Control and Prevention， Mangshi， Yunnan 678400， China
2. Department of Epidemiology， School of Public Health， Key Laboratory of Public Health Safety， Ministy of Education， Fudan University， Shanghai 200032， China
Publication Type:Journal Article
Keywords: HIV-infected person; Burmese; CD4+T cell count; high-risk behavior; round-trip between Myanmar and China
From: Shanghai Journal of Preventive Medicine 2022;34(9):848-853
CountryChina
Language:Chinese
Abstract: ObjectiveTo investigate the demographic characteristics， high-risk behavior and first CD4⁺T cell（CD4 cell） counts among newly reported HIV-infected Burmese in Dehong Dai Jingpo Autonomous Prefecture （Dehong Prefecture） from 2019 to 2020. MethodsA cross-sectional survey was conducted among newly reported HIV-infected Burmese cases in Dehong Prefecture from 2019 to 2020 to collect related information and measure their first CD4 cell counts. ResultsAmong 1 228 HIV-infected Burmese cases， 846 （68.9%） were males and 382 （31.1%） were females； 445 （36.2%） were from Kachin， and 210（17.1%） were from Shan. Of them， 960 cases （78.2%） had participated in the first CD4 cell counts testing， and 405 cases （42.2%） had a first CD4 cell counts <350 cells·μL^-1. In the multivariable logistic regression analysis， age ≥30 years （adjusted OR=1.44， 95%CI： 1.07‒1.92） and history of illicit drug use in Myanmar （adjusted OR=0.41， 95%CI： 0.21‒0.79） were independently associated with first CD4 cell counts <350 cells·μL^-1. ConclusionThe first CD4 cell counts are generally low among newly reported HIV-infected Burmese in Dehong Prefecture， especially those aged ≥ 30 years and with a history of intravenous drug use in Myanmar. Therefore， early detection of HIV infection should be strengthened for timely intervention and treatment management among Burmese.