Clinical Significance of the Application of Thrombelastogram in Perioperative Detection of Esophageal Cancer Patients
- VernacularTitle:血栓弹力图在食管癌患者围手术期检测中的意义
- Author:
Jing-zhuo PANG
1
;
Guo-yong WU
2
;
Min YE
1
;
Wen-guang PANG
1
;
Shi-chao ZHANG
1
;
Cheng-jie CAI
1
Author Information
1. Department of Thoracic Surgery, Central Hospital of Jiangmen, Jiangmen 529030, China
2. Department of Thoracic Surgery, The First Hospital of Sun Yat-sen University, Guangzhou 510080, China
- Publication Type:Journal Article
- Keywords:
esophageal cancer;
thrombelastogram;
hypercoagulability
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2020;41(6):975-980
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 Thrombelastogram(TEG) was used to detect the blood clotting function of patients with esophageal cancer in each stage of perioperative period, so as to understand the change pattern of blood clotting function in patients with esophageal cancer during perioperative period, and to guide the postoperative anticoagulation or hemostasis treatment. 【Methods】 Sixty patients diagnosed with esophageal cancer who underwent surgical treatment between May 2017 and May 2019 in Jiangmen Central Hospital were selected as the experimental group, and 60 cases of healthy physical examination were selected as the normal control group. By contrasting with the normal control group, results of blood sample testing for the experimental group 1 day before, 1 day after operation, and the 7th day postoperative thrombosis elastic figure were used to analyze the change of the esophageal perioperative blood coagulation function. 【Results】 Compared with the control group before surgery, the TEG parameters R, K and LY30 decreased, and Angle, MA and CI increased, with statistically significant differences(P < 0.05). Compared with the normal control group after surgery, the R and K values of TEG parameters in the experimental group decreased significantly, while Angle, MA and CI values increased significantly, with statistically significant differences(P < 0.01), and LY30 values decreased, with statistically significant differences(P < 0.05). Compared with the experimental group before and after surgery, the TEG parameters R and K decreased, and the values of LY30, Angle, MA and CI increased, with no statistically significant difference(P > 0.05). Seven days after the operation and 1 day after the operation, the values of R and K of TEG decreased, and the values of MA and CI increased, with statistically significant differences(P < 0.05) . 【Conclusion】 All patients with esophageal cancer presented hypercoagulability before and after operation.Surgery and anesthesia did not significantly change the coagulation status of esophageal cancer. In the postoperative recovery process, the hypercoagulable state will be more obvious.
