Drug addiction: Brain Plasticity Mechanism and Targeted Intervention
- VernacularTitle:药物成瘾：脑可塑性机制与靶向干预
- Author:
Ti-fei YUAN
1
Author Information
1. Shanghai Key Laboratory of Psychotic Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China
- Publication Type:Journal Article
- Keywords:
drug addiction;
plasticity;
intervention
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2020;41(3):358-362
- CountryChina
- Language:Chinese
-
Abstract:
Drug addiction evokes plasticity changes in multiple circuits of brain regions, accompanied by changes in brain function and formation of addiction memory. Using animal addiction model, combined with electrophysiological recordings and circuit manipulation, we investigated the important role of brain plasticity in drug addiction. With non-invasive brain stimulation combined with electrophysiological recording, we could perform functional mapping of cortical function and plasticity in different addiction patients; this allowed further neuromodulation-based interventions for drug addiction rehabilitation. We conclude that brain plasticity study is important in drug addiction research.
