Selection strategies of hypoglycemic drug for special population with type 2 diabetes mellitus
- VernacularTitle:特殊人群患2型糖尿病的降糖药物选择策略
- Author:
Jinhua GE
1
;
Na LYU
2
;
Zhihai FENG
3
Author Information
1. First College of Clinical Medicine，Henan University of Chinese Medicine，Zhengzhou 450046，China
2. Dept. of Endocrinology，the Affiliated Hospital of Henan Academy of Chinese Medicine，Zhengzhou 450004，China
3. Dept. of Endocrinology，the First Affiliated Hospital of Henan University of Chinese Medicine，Zhengzhou 450099，China
- Publication Type:Journal Article
- Keywords:
type 2 diabetes mellitus;
special population;
hypoglycemic drugs;
selection strategy
- From:
China Pharmacy
2022;33(20):2545-2550
- CountryChina
- Language:Chinese
-
Abstract:
The special population with type 2 diabetes mellitus（T2DM）are different from the ordinary T 2DM patients in terms of drug treatment due to age ，gender，physiological and pathological status . Based on the latest evidence of evidence -based medical evidence ，this article systematically reviews the selection strategies of hypoglycemic drug in special population such as T2DM patients with complications ， elderly patients ， children patients ， pregnant/lactating women ， etc. To formulate an individualized hypoglycemic treatment plan for T 2DM special population ，it is necessary to reasonably select hypoglycemic drugs according to their different characteristics and the latest evidence -based medical evidence ，so as to precisely reduce blood sugar and prevent and delay the occurrence of diabetic complications . For example ，for T 2DM patients with atherosclerotic cardiovascular disease，heart failure ，kidney disease and liver disease ，sodium glucose co -transporter 2 inhibitors or glucagon-like peptide 1 receptor agonists should be used additionally on the basis of metformin ；for T 2DM patients with gastroparesis ，insulin is recommended ；for T2DM patients with hyperuricemia or gout ，hypoglycemic drugs with uric acid lowering effects should be preferred ，and insulin should be used with caution ；for T 2DM patients with osteoporosis ，hypoglycemic drugs that do not affect bone metabolism or have bone protection effects should be selected ；for the elderly patients with T 2DM，it is recommended to give priority to the drugs with low risk of hypoglycemia alone or in combination .
