Preoperative risk factors for the onset of acute Stanford type A aortic dissection in a multicenter study: A retrospective cohort study

Yuduo WU; Ming Gong; Lizhong Sun; Lianjun Huang; Yongmin Liu; Junming Zhu; Tianxiang GU; Ruixin Fan; Ximing Qian; Hongjia Zhang

Return

Preoperative risk factors for the onset of acute Stanford type A aortic dissection in a multicenter study: A retrospective cohort study

VernacularTitle:急性 Stanford A 型主动脉夹层术前危险因素的多中心回顾性队列研究
Author: Yuduo WU ¹ ; Ming GONG ¹ ; Lizhong SUN ¹ ; Lianjun HUANG ¹ ; Yongmin LIU ¹ ; Junming ZHU ¹ ; Tianxiang GU ² ; Ruixin FAN ³ ; Ximing QIAN ⁴ ; Hongjia ZHANG ¹
Author Information

1. Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing Vascular Disease Diagnosis and Treatment Center, Beijing, 100029, P. R. China
2. Department of Cardiac Surgery, The First Affiliated Hospital of China Medical University, Shenyang, 110001, P. R. China
3. Department of Cardiac Surgery, Guangdong Provincial Institute of Cardiovascular Diseases, Guangzhou, 510080, P. R. China
4. Department of Cardiac Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310000, P. R. Chin
Publication Type:Journal Article
Keywords: Acute Stanford type A aortic dissection; risk factors; multi-center study
From: Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2022;29(08):986-991
CountryChina
Language:Chinese
Abstract: Objective To evaluate the preoperative risk factors for acute Stanford type A aortic dissection (ASTAAD) patients in our country by collecting multi-center data. Methods We consecutively enrolled 700 patients who underwent surgery for ASTAAD in the multi-center hospital database from January 2018 to January 2020. According to the ascending aorta size (AAS), the patients were divided into two groups: a group AAS≥55 mm and a group AAS< 55 mm. Univariate and multivariate logistic regression analyses were used to investigate the related preoperative risk factors for the onset of ASTAAD. Results According to the exclusion criteria, a total of 621 patients were finally enrolled, including 453 males and 168 females with an average age of 48.24±11.51 years, and 509 (81.94%) patients had AAS< 55 mm. Univariate and multivariate statistical analyses showed that smoking, hypertension, preoperative cardiac troponin I, and left ventricular ejection fraction were related to the occurrence of ASTAAD. The mortality rate of the patient during hospitalization was 13.04% (81 patients). Conclusion In clinical practice, various preoperative risk factors affect ASTAAD patients, which should be paid attention to. Comprehensive evaluation and an individualized analysis of patients and timely prevention and intervention improve patients' survival rate.