First exploration of postoperative pulmonary complications after transcatheter tricuspid valve replacement and recommendations for rehabilitation: A prospective cohort study
- VernacularTitle:经导管三尖瓣介入术后肺部并发症的初次探索及康复建议：前瞻性队列研究
- Author:
Yuqiang WANG
1
;
Jun SHI
1
;
Lulu LIU
1
;
Zeruxin LUO
2
;
Fengmei ZHANG
1
;
Yingqiang GUO
1
;
Pengming YU
3
,
4
Author Information
1. Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
2. Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
3. 2. Rehabilitation Medicine Center, West China Hospital, Sichuan University, Chengdu, 610041, P. R. China
4. 3. Key Laboratory of Rehabilitation Medicine in Sichuan Province, Chengdu, 610041, P. R. China
- Publication Type:Journal Article
- Keywords:
Transcatheter tricuspid valve replacement;
postoperative pulmonary complications;
tricuspid regurgitation;
prerehabilitation;
prospective cohort study
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(08):963-970
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the morbidity of postoperative pulmonary complications (PPCs) in patients after transcatheter tricuspid valve replacement (TTVR). Methods A prospective cohort study enrolled 19 patients who were diagnosed with severe or greater tricuspid regurgitation in West China Hospital from October 11, 2020 to March 1, 2021, and would receive TTVR using LuX-valve for valve replacement. The patients were divided into a PPCs group and a non-PPCs group according to the presence of PPCs. The incidence of PPCs after tricuspid valve intervention between the two groups was compared. Results Of 19 patients diagnosed with severe or greater tricuspid regurgitation registered in the database, 17 met the inclusion criteria, including 15 females and 2 males, with a mean age of 68.4±8.0 years. PPCs occurred in 9 of 17 (52.9%) patients. At discharge, compared with the non-PPCs group, the PPCs group had a longer postoperative hospital stay [11.0 (10.0, 17.0) d vs. 7.5 (7.0, 8.0) d, P=0.01], longer ICU stay [72.0 (45.5, 95.0) h vs. 20.5 (16.0, 22.8) h, P<0.01], and more hospital cost [74.3 (65.9, 98.3) thousand yuan vs. 52.6 (44.2, 57.4) thousand yuan, P<0.01]. At 30 days of follow-up, the PPCs group was found that the rate of New York Heart Association cardiac function≥class Ⅲ (66.7% vs. 12.5%, P<0.01) was higher, the six-minute walk distance (170.2±169.3 m vs. 377.9±80.5 m, P<0.01) was shorter and Kansas City Cardiomyopathy Questionnaire heart failure score (40.9±31.2 vs. 80.4±5.8, P<0.01) was less than those of the non-PPCs group. Conclusion PPCs are common in the patients undergoing TTVR and severely affect patients' cardiac function, exercise function and quality-of-life recovery. Proactive preoperative intervention as well as early postoperative rehabilitation management should be provided to those at high risk of PPCs.
