Use of opioid analgesics during postoperative hospitalization in patients undergoing lung resection and its influencing factors: A retrospective cohort study
- VernacularTitle:肺切除患者术后住院期间阿片类药物应用情况及其影响因素的回顾性队列研究
- Author:
Yuanqiang ZHANG
1
,
2
;
Xing WEI
3
,
4
;
Shaohua XIE
3
,
4
;
Yaqin WANG
3
,
4
;
Jia LIAO
3
,
4
;
Wei XU
5
;
Yang PU
5
;
Qiuling SHI
4
,
6
,
7
;
Qiang LI
3
,
4
;
Wei DAI
3
,
4
;
Jifu DONG
4
,
8
Author Information
1. Department of Cardiothoracic Surgery, Zigong First People'
2. s Hospital, Zigong, 643000, Sichuan, P. R. China
3. Department of Thoracic Surgery, Sichuan Cancer Hospital &
4. Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610041, P. R. China
5. School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, P. R. China
6. 3. School of Public Health and Management, Chongqing Medical University, Chongqing, 400016, P. R. China
7. 4. Center for Cancer Prevention Research, Sichuan Cancer Hospital &
8. Department of Anesthesiology, Sichuan Cancer Hospital &
- Publication Type:Journal Article
- Keywords:
Lung cancer;
surgery;
postoperative hospitalization;
pain;
opioid analgesics;
influencing factor
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(07):909-913
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the use of opioid analgesics during the postoperative hospitalization in patients undergoing lung resection and analyse its influencing factors. Methods The clinical data of 450 patients undergoing lung resection in Sichuan Cancer Hospital among a multicenter symptom research database (CN-PRO-Lung 1) between November 2017 and January 2020 were analyzed. There were 248 males and 202 females with an average age of 54.7±10.3 years. Results A total of 448 (99.6%) patients used opioid analgesics. The average daily morphine equivalent dose during the postoperative hospitalization was 48.9 mg. There were statistical differences in postoperative morphine equivalent dose across patients with different sex, age, highest level of education, Charlson Comorbidity Index score, surgical approach, surgical type, operative time, postoperative hospital stay and grade of postoperative complications (all P<0.05). Multivariate analysis showed that sex, surgical approach and postoperative hospital stay were independent influencing factors for morphine use during the postoperative hospitalization in patients undergoing lung resection (all P<0.05). Conclusion In clinical practice, attention should be paid to postoperative pain for male patients, as well as to promote the application of minimally invasive surgery, and to shorten the length of postoperative hospital stay, in order to ultimately reduce the use of opioids.
