Cryomaze ablation in treatment of elderly patients with mitral valve diseases combined with persistent or long-term persistent atrial fibrillation: A propensity-score matching study
- VernacularTitle:冷冻消融迷宫手术治疗老年二尖瓣病变合并持续性或长期持续性心房颤动的倾向性评分匹配分析
- Author:
Xinting CHEN
1
,
2
;
Huishan WANG
3
;
Jinsong HAN
3
;
Zongtao YIN
3
;
Yingjie ZHANG
3
;
Yu LUO
3
;
Hanqing LIANG
3
;
Zhipeng GUO
3
Author Information
1. 1. Graduate School, Jinzhou Medical University, Shenyang, 110016, P. R. China
2. 2. Department of Cardiothoracic Surgery, General Hospital of Northern Theater Command, Shenyang, 110016, P. R. China
3. Department of Cardiothoracic Surgery, General Hospital of Northern Theater Command, Shenyang, 110016, P. R. China
- Publication Type:Journal Article
- Keywords:
Cryoablation;
Maze procedure;
elderly patients;
mitral valve disease;
atrial fibrillation;
propensity-score matching study
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2022;29(06):748-754
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the safety and efficacy of mitral valve surgery and cryoablation in elderly patients with mitral valve disease and persistent or long-term persistent atrial fibrillation. Methods From May 2014 to July 2018, 144 patients with mitral valve diseases combined with persistent or long-term persistent atrial fibrillation in the Department of Cardiothoracic Surgery, General Hospital of Northern Theater Command were selected. Among them, there were 69 patients in a non-elderly group (<60 years) including 18 males and 51 females aged 52.07±5.56 years, and 75 patients in an elderly group (≥60 years) including 32 males and 43 females aged 65.23±4.29 years. A propensity-score matching (PSM) study was conducted to eliminate confounding factors. Both groups underwent mitral valve surgery and cryoablation at the same time. A 2-year follow-up was conducted after discharge from the hospital, and the perioperative and postoperative efficacy indexes were compared between the two groups. Results After PSM analysis, there were 56 patients in each group. The sinus rhythm conversion rate of the two groups at each follow-up time point was above 85%, and the cardiac function was graded asⅠorⅡ, which was significantly improved compared with that before the surgery, but there was no statistical difference between the two groups (P>0.05). Among the perioperative indicators of the two groups, the elderly group had more coronary artery bypass graft surgeries and longer postoperative ICU stay time compared with the non-elderly group (P<0.05), and the differences in other indicators were not statistically different (P>0.05). Conclusion The mitral valve surgery and cryoablation in elderly patients with mitral valve diseases combined with persistent or long-term persistent atrial fibrillation are safe, and the short-term outcome is satisfactory.