Anticoagulants for artificial liver support therapy: Application advances and selection strategies
10.3969/j.issn.1001-5256.2022.10.038
- VernacularTitle:人工肝治疗的抗凝剂应用进展及选择策略
- Author:
Yuanji MA
1
;
Lingyao DU
1
;
Lang BAI
1
;
Hong TANG
1
Author Information
1. Center of Infectious Diseases, West China Hospital of Sichuan University, Chengdu 610041, China
- Publication Type:Reviews
- Keywords:
Liver Failure;
Liver, Artificial;
Anticoagulants;
Therapeutics
- From:
Journal of Clinical Hepatology
2022;38(10):2396-2401
- CountryChina
- Language:Chinese
-
Abstract:
Coagulation disorder is one of the characteristics of liver failure, leading to an unstable and vulnerable "rebalance" state of coagulation function, which may be easily broken by internal or external factors. Anticoagulants are often required during artificial liver support therapy for patients with liver failure, which may break the "rebalance" state and result in bleeding events. This article reviews the methods for evaluating coagulation status in liver failure, the features of available anticoagulants, and the advances in the application of such anticoagulants in artificial liver support therapy and discusses the anticoagulation management and selection strategy for artificial liver support therapy with reference to the selection experience of West China Hospital of Sichuan University.
