Evidence-based pre -prescribing review to standardize off -label drug use for sleep disorders
- VernacularTitle:基于循证证据的睡眠障碍超说明书用药处方前置审核
- Author:
Jing MA
1
;
Chen LI
1
Author Information
1. Dept. of Pharmacy，Daping Hospital，Army Medical University，Chongqing 400010，China
- Publication Type:Journal Article
- Keywords:
off-label drug use;
sleep disorder;
pre-prescribing review;
evidence-based medicine;
review rules
- From:
China Pharmacy
2022;33(19):2414-2417
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To provide reference for standardizing off -label drug use for sleep disorders in hospitals . METHODS The off -label drug use for sleep disorders in our hospital was analyzed statistically ，and then was evaluated with evidence -based medical evidence . The records that met the filing standards for off -label drug use should be filed ，and the drug review rules should be modified in the pre -prescribing review system . The blocking rules in the pre -prescribing review system were set up for unreasonable off -label drug use . RESULTS Off-label drug use for sleep disorders in our hospital accounted for 36.92% of total number of prescriptions ，including drug use of off -indication，over-frequency，over-dose. After the pharmacists modified the drug review rules ，the rational off -label drug use system would be automatically reviewed and approved ，and the unreasonable off -label drug use system would be intercepted . CONCLUSIONS There is a certain rationality in off -label drug use for sleep disorders . The pharmacists can further standardize off -label drug use for sleep disorders by continuously improving the standardized management of off-label drug use and revising the drug review rules of pre -prescribing review system ，so as to ensure the safe ，reasonable and effective use of drugs related to sleep disorders .
