Study on quality standard of Onosma echioides
- VernacularTitle:蓝蓟滇紫草的质量标准研究
- Author:
Qianqian WANG
1
;
Kejian PANG
1
;
Wei GAO
1
;
Ke ZHANG
1
;
Hanying CHEN
1
;
Bo ZHANG
1
Author Information
1. School of Pharmacy，Shihezi University/Key Laboratory of Xinjiang Phytomedicine Resources and Utilization，Ministry of Education，Xinjiang Shihezi 832002，China
- Publication Type:Journal Article
- Keywords:
Onosma echioides;
quality standard;
Arnebiae Radix;
hydroxynaphthoquinone;
alkannin;
β，β′-dimethylacry-
- From:
China Pharmacy
2022;33(19):2321-2325
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To establish the quality standard of Onosma echioides . METHODS Sixteen batches of O. echioides from different sources were collected to observe their appearance ，microscopic powder identification ，and TLC identification ；the impurity，moisture，total ash and acid -insoluble ash of the medicinal materials were examined . The total pigment content of hydroxynaphthoquinone in O. echioides was determined by UV -visible spectrophotometry ；the contents of alkannin and β，β′- dimethylacrylalkannin in O. echioides were determined by HPLC . RESULTS Medicinal material and powder of O. echioides were purplish red ；non-glandular single cells ，embolized cells ，parenchyma cells ，reticulate ducts could be seen microscopically . TLC results showed that the color and change of the spots in the chromatogram of test sample were consistent with that of the control . The contents of moisture ，total ash and acid insoluble ashshall not exceed 13.0%，18.0%，6.0%. The total pigment content of hydroxynaphthoquinone should not be less than 0.80%. The content of alkannin was recommended to be no less than 0.06 mg/g. The content of β，β′-dimethylacrylalkannin was recommended to be no less than 0.60 mg/g. CONCLUSIONS The established standard can provide reference for the scientific evaluation of the quality of the medicinal materials of O. echioides.
