Signal Pathway of Cyclooxygenase- 2/Prostaglandin E2 and Phosphoinositide- 3 Kinase/Akt in Osteotendinous Junction (review)
10.3969/j.issn.1006-9771.2014.01.016
- VernacularTitle:环氧化酶-2/前列腺素E2与磷脂酰肌醇-3 激酶/Akt 信号通路在腱骨连接处作用的相关研究
- Author:
Jing WANG
;
Guoxiang WANG
- Publication Type:Journal Article
- Keywords:
cyclooxygenase-2, prostaglandin E2, phosphoinositide-3 kinase, Akt, osteotendinous junction, review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2014;20(1):59-62
- CountryChina
- Language:Chinese
-
Abstract:
Osteotendinous junction (OTJ) is the main structure of tendinopathy. Cyclooxygenase-2/prostaglandin E2 (COX-2/PGE2) and phosphoinositide-3 kinase (PI3K)/Akt is active under the stress, and expresses in OTJ. This article summarized the role of these two signaling pathways in OTJ.