Risk factors of chronic obstructive pulmonary disease complicated by invasive pulmonary aspergillosis
10.19485/j.cnki.issn2096-5087.2022.10.006
- Author:
Minchao CHEN
;
Chunling WU
;
Jianying ZHOU
- Publication Type:Journal Article
- Keywords:
chronic obstructive pulmonary disease；invasive pulmonary aspergillosis；risk factor
- From:
Journal of Preventive Medicine
2022;34(10):1002-1006
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the risk factors of chronic obstructive pulmonary disease (COPD) complicated by invasive pulmonary aspergillosis (IPA), so as to provide insights into prevention of IPA among COPD patients.
Methods:The COPD patients complicated by IPA hospitalized in Yiwu Central Hospital from 2017 to 2021 were recruited as the case group, while COPD patients without IPA during the same study period served as controls. Participants' general information, laboratory tests, comorbidities and treatments were collected. The risk factors of COPD complicated by IPA were identified using a multivariable logistic regression model.
Results:There were 30 participants in the case group and 30 in the control group, including 22 men and 8 women in each group and with a mean age of (75.00±10.00) and (74.00±10.00) years, respectively. There were 27 (90.00%) and 19 (63.33%) cases with stage 3 and higher COPD in the case and control groups, and the mean duration of hospital stay in the past one year was (12.89±4.88) and (8.59±3.85) days in the case and control groups, respectively. Multivariable logistic regression analysis identified long duration of hospital stay in the past one year (OR=1.230, 95%CI: 1.011-1.498), stage 3 and higher COPD (OR=18.637, 95%CI: 1.415-245.402) as risk factors of COPD complicated by IPA.
Conclusions:Duration of hospital stay in the past one year and severity of COPD are risk factors for COPD complicated by IPA.
- Full text:慢性阻塞性肺疾病合并侵袭性肺曲霉病的危险因素研究.pdf
