Application of resting-state functional magnetic resonance imaging in acute mild traumatic brain injury
10.3969/j.issn.1006-9771.2022.09.012
- VernacularTitle:静息态脑功能磁共振成像在急性轻型脑外伤中的应用
- Author:
Xiaoyu ZHANG
1
;
Fan YANG
1
;
Jianzhong WEN
2
;
Weiyong YU
1
Author Information
1. Capital Medical University School of Rehabilitation Medicine, Beijing 100068, China
2. Sports Hospital, Institute of Sports Medicine, General Administration of Sport of China, Beijing 100763, China
- Publication Type:Journal Article
- Keywords:
traumatic brain injury;
functional magnetic resonance imaging;
amplitude of low-frequency fluctuation;
cognition
- From:
Chinese Journal of Rehabilitation Theory and Practice
2022;28(9):1084-1088
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo apply resting-state functional magnetic resonance imaging in acute mild traumatic brain injury. MethodsFrom May, 2019 to May, 2021, 47 cases with acute mild traumatic brain injury in Beijing Bo'ai Hospital were selected as observation group, and 50 healthy people who visited for routine physical examination during the same period were as control group. They were scanned with resting-state functional magnetic resonance imaging to measure amplitude of low-frequency fluctuation (ALFF), and they were assessed with Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA) and Rivermead Behavioural Memory Test (RBMT). ResultsCompared with the control group, the scores of MMSE, MoCA and RBMT decreased in the observation group (t > 18.138, P < 0.001); while ALFF decreased in the brain areas of posterior cerebellar lobe, cerebellar tonsils, lower half moon lobules, right superior temporal gyrus, right middle temporal gyrus, right parietal lobe and right central posterior gyrus, etc; and ALFF increased in the brain areas of marginal lobe, cingulate gyrus, precuneus, left cerebellar, right superior temporal gyrus, right middle temporal gyrus, right superior frontal gyrus, right middle frontal gyrus, right inferior frontal gyrus, etc. ConclusionThere are disorders in multiple brain areas for patients after acute mild traumatic brain injury, which may associate to the cognitive impairment.
